NEJM: Antipsychotics really suck

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EKR

on September 19, 2005 8:28 PM Permalink | Comments (2) | TrackBacks (6) |

Lieberman et al. reports the somewhat surprising result that the 2nd generation antipsychotics are only marginally better than the 1st generatio—or rather we should say that they suck marginally less. As someone who hasn't been following this field, what's surprising is how high the discontinuation rate: 74% overall and 64% for the best drug tested: olanzapine. Basically, if you're schizophrenic, the options are not good.

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2 Comments

By Andrew on September 20, 2005 7:50 AM

There just isn't enough money in Schizophrenia.

By Eliot Gelwan/Follow Me Here on September 20, 2005 10:12 PM

I have commented here on your post:

http://theworld.com/~emg/2005_09_01_blog_archive.html#112726583823602189

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